[KO Validated] HIF1AN/FIH1 Rabbit Monoclonal Antibody (CAB3701)
- SKU:
- CAB3701
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | [KO Validated] HIF1AN/FIH1 Rabbit Monoclonal Antibody |
SKU: | CAB3701 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human HIF1AN/FIH1 (Q9NWT6). |
Sequence: | MAAT AAEA VASG SGEP REEA GALG PAWD ESQL RSYS FPTR PIPR LSQS DPRA EELI ENEE PVVL TDTN LVYP ALKW DLEY LQEN IGNG DFSV YSAS THKF |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | FIH1; H1 |
Positive Sample: | U-87MG,293T |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus, perinuclear region. |
Calculated MW: | 41kDa |
Observed MW: | 40kDa |
Enables several functions, including 2-oxoglutarate-dependent dioxygenase activity; NF-kappaB binding activity; and transition metal ion binding activity. Involved in several processes, including negative regulation of Notch signaling pathway; negative regulation of transcription from RNA polymerase II promoter in response to hypoxia; and protein hydroxylation. Located in cytosol; nucleoplasm; and perinuclear region of cytoplasm. Colocalizes with nucleus.
Purification Method: | Affinity purification |
Gene ID: | 55662 |
Clone Number: | ARC0826 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |