[KO Validated] HDAC1 Rabbit Monoclonal Antibody (CAB19571)
- SKU:
- CAB19571
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | [KO Validated] HDAC1 Rabbit Monoclonal Antibody |
SKU: | CAB19571 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 350-450 of human HDAC1 (Q13547). |
Sequence: | MTNQ NTNE YLEK IKQR LFEN LRML PHAP GVQM QAIP EDAI PEES GDED EDDP DKRI SICS SDKR IACE EEFS DSEE EGEG GRKN SSNF KKAK RVKT EDEK E |
Tested Applications: | WB IHC-P IF/ICC IP ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | HD1; RPD3; KDAC1; GON-10; RPD3L1; C1 |
Positive Sample: | 293T,MCF7,NIH/3T3,Mouse thymus,Mouse testis,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 55kDa |
Observed MW: | 65kDa |
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.
Purification Method: | Affinity purification |
Gene ID: | 3065 |
Clone Number: | ARC0050 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |