The GSTO1 Polyclonal Antibody (CAB19892) is a powerful tool for researchers studying glutathione S-transferase omega 1 (GSTO1), an enzyme involved in the detoxification of xenobiotics and oxidative stress response. This rabbit polyclonal antibody shows high specificity and sensitivity for detecting GSTO1 in human samples, making it ideal for use in Western blot applications.GSTO1 is known for its role in protecting cells from damage caused by reactive oxygen species and toxic compounds. Dysfunction of GSTO1 has been linked to various diseases, including neurodegenerative disorders and cancer.
By targeting GSTO1, researchers can gain valuable insights into the mechanisms underlying these conditions and potentially identify new therapeutic targets.With its ability to selectively bind to GSTO1, this antibody enables precise detection and quantification of the enzyme in different cell types and tissues. Whether investigating the role of GSTO1 in drug metabolism, oxidative stress, or disease progression, this antibody offers a reliable tool for advancing research in the fields of biochemistry, pharmacology, and toxicology.
Product Name:
[KO Validated] GSTO1 Rabbit Polyclonal Antibody
SKU:
CAB19892
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-241 of human GSTO1 (NP_004823.1).
The protein encoded by this gene is an omega class glutathione S-transferase (GST) with glutathione-dependent thiol transferase and dehydroascorbate reductase activities. GSTs are involved in the metabolism of xenobiotics and carcinogens. The encoded protein acts as a homodimer and is found in the cytoplasm. Three transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
9446
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and GSTO1 knockout (KO) 293T cells, using [KO Validated] GSTO1 Rabbit pAb (CAB19892) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
