The GSK3 alpha Rabbit Monoclonal Antibody (CAB19060) is a powerful tool for researchers studying GSK3 alpha, a key player in various cellular processes such as cell growth, differentiation, and metabolism. This antibody, produced in rabbits, is highly specific to GSK3 alpha and has been rigorously validated for use in Western blot applications.GSK3 alpha is a serine/threonine kinase that is involved in multiple signaling pathways and has been implicated in various diseases including cancer, diabetes, and neurodegenerative disorders.
By targeting GSK3 alpha with this antibody, researchers can gain valuable insights into its role in disease progression and potentially identify new therapeutic targets.The GSK3 alpha Rabbit Monoclonal Antibody is a reliable tool for studying the function and regulation of GSK3 alpha in different cell types and disease models. With its high specificity and sensitivity, this antibody is essential for advancing research in the fields of cell biology, biochemistry, and drug discovery.
Product Name:
[KO Validated] GSK3α Rabbit Monoclonal Antibody
SKU:
CAB19060
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GSK3α (P49840).
This gene encodes a multifunctional Ser/Thr protein kinase that is implicated in the control of several regulatory proteins including glycogen synthase, and transcription factors, such as JUN. It also plays a role in the WNT and PI3K signaling pathways, as well as regulates the production of beta-amyloid peptides associated with Alzheimer's disease.
Purification Method:
Affinity purification
Gene ID:
2931
Clone Number:
ARC0462
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and GSK3α knockout (KO) HeLa cells, using [KO Validated] GSK3α Rabbit mAb (CAB19060) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
