[KO Validated] GRK2 Rabbit Monoclonal Antibody (CAB4443)
- SKU:
- CAB4443
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- ADRBK1
- BARK1
- BETA-ARK1
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | [KO Validated] GRK2 Rabbit Monoclonal Antibody |
SKU: | CAB4443 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 590-689 of human GRK2 (P25098). |
Sequence: | WRGE GEAP QSLL TMEE IQSV EETQ IKER KCLL LKIR GGKQ FILQ CDSD PELV QWKK ELRD AYRE AQQL VQRV PKMK NKPR SPVV ELSK VPLV QRGS ANGL |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | BARK1; ADRBK1; BETA-ARK1; K2 |
Positive Sample: | HeLa,Mouse brain,Mouse spleen,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm. |
Calculated MW: | 80kDa |
Observed MW: | 80kDa |
This gene encodes a member of the G protein-coupled receptor kinase family of proteins. The encoded protein phosphorylates the beta-adrenergic receptor as well as a wide range of other substrates including non-GPCR cell surface receptors, and cytoskeletal, mitochondrial, and transcription factor proteins. Data from rodent models supports a role for this gene in embryonic development, heart function and metabolism. Elevated expression of this gene has been observed in human patients with heart failure and Alzheimer's disease.
Purification Method: | Affinity purification |
Gene ID: | 156 |
Clone Number: | ARC1013 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |