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[KO Validated] Glutamine Synthetase (GLUL) Rabbit Polyclonal Antibody (CAB5437)

SKU:
CAB5437
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cardiovascular
  • KO Validated Antibodies 1 Anti-GLUL Antibody CAB5437KO Validated
  • KO Validated Antibodies 1 Anti-GLUL Antibody CAB5437KO Validated
  • KO Validated Antibodies 1 Anti-GLUL Antibody CAB5437KO Validated
  • KO Validated Antibodies 1 Anti-GLUL Antibody CAB5437KO Validated
  • KO Validated Antibodies 1 Anti-GLUL Antibody CAB5437KO Validated
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:[KO Validated] Glutamine Synthetase (GLUL) Rabbit Polyclonal Antibody
SKU:CAB5437
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-373 of human Glutamine Synthetase (GLUL) (NP_002056.2).
Sequence:MTTS ASSH LNKG IKQV YMSL PQGE KVQA MYIW IDGT GEGL RCKT RTLD SEPK CVEE LPEW NFDG SSTL QSEG SNSD MYLV PAAM FRDP FRKD PNKL VLCE VFKY NRRP AETN LRHT CKRI MDMV SNQH PWFG MEQE YTLM GTDG HPFG WPSN GFPG PQGP YYCG VGAD RAYG RDIV EAHY RACL YAGV KIAG TNAE VMPA QWEF QIGP CEGI SMGD HLWV ARFI LHRV CEDF GVIA TFDP KPIP GNWN GAGC HTNF STKA MREE NGLK YIEE AIEK LSKR HQYH IRAY DPKG GLDN ARRL TGFH ETSN INDF SAGV ANRS ASIR IPRT VGQE KKGY FEDR RPSA NCDP FSVT EALI RTCL LNET GDEP FQYK N
Tested Applications:WB IHC-P IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200
Synonyms:GS; GLNS; PIG43; PIG59; L)
Positive Sample:Mouse brain,Rat brain
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Mitochondrion.
Calculated MW:42kDa
Observed MW:42kDa

The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base homeostasis, cell signaling, and cell proliferation. Glutamine is an abundant amino acid, and is important to the biosynthesis of several amino acids, pyrimidines, and purines. Mutations in this gene are associated with congenital glutamine deficiency, and overexpression of this gene was observed in some primary liver cancer samples. There are six pseudogenes of this gene found on chromosomes 2, 5, 9, 11, and 12. Alternative splicing results in multiple transcript variants.

Purification Method:Affinity purification
Gene ID:2752
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using Glutamine Synthetase (GLUL) Rabbit pAb (CAB5437) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.

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