The Guanine Deaminase Polyclonal Antibody (CAB6441) is a valuable tool for researchers studying guanine deaminase, an enzyme involved in the metabolism of purine nucleotides. This antibody, generated in rabbits, exhibits high reactivity with human samples and is suitable for Western blot applications, enabling the detection and analysis of guanine deaminase in various biological samples.Guanine deaminase plays a key role in the purine salvage pathway, converting guanine to xanthine and ammonia. Dysregulation of this enzyme has been implicated in various diseases, including metabolic disorders and cancer.
By targeting guanine deaminase with this antibody, researchers can gain insights into its functions and potential therapeutic applications in these disease contexts.The Guanine Deaminase Polyclonal Antibody is a valuable tool for investigating the role of guanine deaminase in cellular processes and disease pathways, making it an essential reagent for studies in biochemistry, pharmacology, and biomedical research.
Product Name:
GDA Rabbit Polyclonal Antibody
SKU:
CAB6441
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 165-454 of human GDA (NP_004284.1).
This gene encodes an enzyme responsible for the hydrolytic deamination of guanine. Studies in rat ortholog suggest this gene plays a role in microtubule assembly. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
9615
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using GDA Antibody (CAB6441) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
