The GCN1L1 Polyclonal Antibody (CAB19851) is a valuable tool for researchers studying the GCN1L1 protein, which plays a key role in cellular processes such as protein synthesis and response to stress. This antibody, produced in rabbits, exhibits high specificity for human samples and has been validated for use in Western blot applications.GCN1L1 is a crucial component of the integrated stress response pathway, which helps cells adapt to various stressors and maintain homeostasis. Dysregulation of this pathway has been implicated in diseases such as cancer, neurodegenerative disorders, and metabolic syndromes.
By targeting GCN1L1 with this antibody, researchers can gain insights into its function and potential therapeutic applications in these disease contexts.This GCN1L1 Polyclonal Antibody is an essential tool for studies in molecular biology, cell biology, and pathology. Its ability to specifically detect GCN1L1 protein levels in various cell types makes it ideal for investigating the mechanisms underlying cellular stress responses and identifying novel therapeutic targets. Gain a deeper understanding of GCN1L1 and its role in disease pathology with this reliable and validated antibody.
Product Name:
[KO Validated] GCN1L1 Rabbit Polyclonal Antibody
SKU:
CAB19851
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 2462-2671 of human GCN1L1 (NP_006827.1).
Enables RNA binding activity and cadherin binding activity. Predicted to be involved in cellular response to leucine starvation and positive regulation of transcription from RNA polymerase II promoter in response to stress. Located in cytosol.
Purification Method:
Affinity purification
Gene ID:
10985
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and GCN1L1 knockout (KO) 293T cells, using [KO Validated] GCN1L1 Rabbit pAb (CAB19851) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30S.
