[KO Validated] FUS Rabbit Polyclonal Antibody (CAB5921)
- SKU:
- CAB5921
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | [KO Validated] FUS Rabbit Polyclonal Antibody |
SKU: | CAB5921 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 297-526 of human FUS (NP_004951.1). |
Sequence: | TIES VADY FKQI GIIK TNKK TGQP MINL YTDR ETGK LKGE ATVS FDDP PSAK AAID WFDG KEFS GNPI KVSF ATRR ADFN RGGG NGRG GRGR GGPM GRGG YGGG GSGG GGRG GFPS GGGG GGGQ QRAG DWKC PNPT CENM NFSW RNEC NQCK APKP DGPG GGPG GSHM GGNY GDDR RGGR GGYD RGGY RGRG GDRG GFRG GRGG GDRG GFGP GKMD SRGE HRQD RRER PY |
Tested Applications: | WB IF/ICC IP ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:100 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | TLS; ALS6; ETM4; FUS1; POMP75; altFUS; HNRNPP2; US |
Positive Sample: | U-937,Jurkat |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 53kDa |
Observed MW: | 70kDa |
This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6.
Purification Method: | Affinity purification |
Gene ID: | 2521 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |