Anti-FIBP Antibody (CAB19908)[KO Validated]
- SKU:
- CAB19908
- Product Type:
- Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Anti-FIBP Antibody (CAB19908)[KO Validated]
The FIBP Polyclonal Antibody (CAB19908) is a valuable tool for researchers studying FIBP, a protein involved in various cellular processes, including cell proliferation and tumorigenesis. This antibody, raised in rabbits and rigorously validated, is highly specific for FIBP in human samples and is suitable for Western blot applications.FIBP, also known as FUSE-binding protein, plays a crucial role in regulating gene expression and DNA replication, making it a key player in cancer research and other fields.
By targeting FIBP with this polyclonal antibody, researchers can study its function and molecular interactions in different cell types, providing valuable insights into its potential as a therapeutic target in cancer and other diseases. This antibody is an essential tool for scientists looking to unravel the complexities of FIBP and its implications in various cellular processes.
| Antibody Name: | Anti-FIBP Antibody [KO Validated] |
| Antibody SKU: | CAB19908 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human FIBP. |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Rat |
| Positive Samples: | HeLa |
| Immunogen: | Recombinant protein of human FIBP. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 9158 |
| Uniprot: | O43427 |
| Cellular Location: | Endomembrane system, Nucleus, Peripheral membrane protein |
| Calculated MW: | 41kDa |
| Observed MW: | 43KDa |
![Anti-FIBP Antibody [KO Validated] (CAB19908)](https://cdn11.bigcommerce.com/s-h68l9z2lnx/product_images/j/633/A19908_1__46176.jpg) | Western blot analysis of extracts from normal (control) and FIBP knockout (KO) HeLa cells, using FIBP antibody (CAB19908) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
| Synonyms: | FIBP, FGFIBP, FIBP-1, TROFAS |
| Background: | Acidic fibroblast growth factor is mitogenic for a variety of different cell types and acts by stimulating mitogenesis or inducing morphological changes and differentiation. The FIBP protein is an intracellular protein that binds selectively to acidic fibroblast growth factor (aFGF). It is postulated that FIBP may be involved in the mitogenic action of aFGF. Two transcript variants encoding different isoforms have been found for this gene. |
| UniProt Protein Function: | FIBP: May be involved in mitogenic function of FGF1. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 11q13.1 Cellular Component: nucleoplasm; membrane; mitochondrion; endomembrane system; nucleus Molecular Function:fibroblast growth factor binding Biological Process: fibroblast growth factor receptor signaling pathway |
| NCBI Summary: | Acidic fibroblast growth factor is mitogenic for a variety of different cell types and acts by stimulating mitogenesis or inducing morphological changes and differentiation. The FIBP protein is an intracellular protein that binds selectively to acidic fibroblast growth factor (aFGF). It is postulated that FIBP may be involved in the mitogenic action of aFGF. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O43427 |
| NCBI GenInfo Identifier: | 13431517 |
| NCBI Gene ID: | 9158 |
| NCBI Accession: | O43427.3 |
| UniProt Secondary Accession: | O43427,Q27Q85, Q6IBQ3, Q9HD65, A8K0J7, |
| UniProt Related Accession: | O43427 |
| Molecular Weight: | 364 |
| NCBI Full Name: | Acidic fibroblast growth factor intracellular-binding protein |
| NCBI Synonym Full Names: | fibroblast growth factor (acidic) intracellular binding protein |
| NCBI Official Symbol: | FIBPÂ Â |
| NCBI Official Synonym Symbols: | FGFIBP; FIBP-1Â Â |
| NCBI Protein Information: | acidic fibroblast growth factor intracellular-binding protein; aFGF intracellular-binding protein; FGF-1 intracellular-binding protein |
| UniProt Protein Name: | Acidic fibroblast growth factor intracellular-binding protein |
| UniProt Synonym Protein Names: | FGF-1 intracellular-binding protein |
| Protein Family: | Acidic fibroblast growth factor intracellular-binding protein |
| UniProt Gene Name: | FIBPÂ Â |
| UniProt Entry Name: | FIBP_HUMAN |
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