The KO Validated FGF2 Rabbit Monoclonal Antibody is a powerful tool for researchers studying fibroblast growth factor 2 (FGF2), a key player in various cellular processes such as cell proliferation, differentiation, and angiogenesis. This antibody, developed and validated in rabbit models, exhibits high specificity and sensitivity towards FGF2, making it an ideal choice for immunohistochemistry, immunofluorescence, and flow cytometry applications.FGF2, a member of the FGF family, is known for its role in promoting cell growth and survival, making it a target of interest in cancer research and regenerative medicine.
The KO Validated FGF2 Rabbit Monoclonal Antibody enables the precise detection and localization of FGF2 in various tissue samples, providing valuable insights into its function and potential therapeutic applications.Whether investigating the role of FGF2 in tumor growth, tissue regeneration, or developmental processes, this antibody offers reliable and reproducible results, giving researchers a deeper understanding of FGF2 biology and its implications in health and disease. Trust the KO Validated FGF2 Rabbit Monoclonal Antibody for accurate and insightful analyses in your research endeavors.
Product Name:
[KO Validated] FGF2 Rabbit Monoclonal Antibody
SKU:
CAB11488
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human FGF2 (NP_001997.5).
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.
Purification Method:
Affinity purification
Gene ID:
2247
Clone Number:
ARC0618
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of lysates from SKOV3 cells, using FGF2 Rabbit mAb (CAB11488) at 1：1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
