The ERP29 Polyclonal Antibody (CAB7959) is a vital tool for research involving ERP29, a protein associated with endoplasmic reticulum stress response and protein folding. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the ERP29 protein, it allows for precise detection and analysis in a variety of cell types, making it an essential component for studies in cellular biology and disease mechanisms.ERP29 is a key player in maintaining cellular homeostasis by aiding in proper protein folding and quality control in the endoplasmic reticulum.
Dysregulation of ERP29 has been linked to diseases such as cancer, neurodegenerative disorders, and diabetes, highlighting the importance of understanding its function and regulation. The ERP29 Polyclonal Antibody provides researchers with a valuable tool to further investigate the role of ERP29 in these pathological conditions and potentially uncover novel therapeutic strategies.
Product Name:
[KO Validated] ERp29 Rabbit Polyclonal Antibody
SKU:
CAB7959
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 33-261 of human ERp29 (NP_006808.1).
This gene encodes a protein which localizes to the lumen of the endoplasmic reticulum (ER). It is a member of the protein disulfide isomerase (PDI) protein family but lacks an active thioredoxin motif, suggesting that this protein does not function as a disulfide isomerase. The canonical protein dimerizes and is thought to play a role in the processing of secretory proteins within the ER. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
10961
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using ERp29 Rabbit pAb (CAB7959) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates / proteins: 25 μg per lane.Blocking buffer: 3 % nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
