The EIF3H Polyclonal Antibody (CAB18026) is a valuable tool for researchers studying EIF3H, a subunit of the eukaryotic translation initiation factor 3 (eIF3) complex essential for protein synthesis. This rabbit polyclonal antibody is highly specific and reactive with EIF3H in human samples, validated for use in Western blot applications. By targeting EIF3H, researchers can analyze its expression and function in various cell types, providing insights into translational regulation and its role in cellular processes.
EIF3H is a key player in protein synthesis, controlling the initiation of mRNA translation and influencing gene expression. Dysregulation of EIF3H has been linked to cancer progression and other diseases, making it a promising target for therapeutic interventions. By using the EIF3H Polyclonal Antibody, researchers can investigate the molecular mechanisms underlying EIF3H function and its potential implications in disease pathology. Explore the complexities of translation control with this reliable antibody tool.
Product Name:
[KO Validated] EIF3H Rabbit Polyclonal Antibody
SKU:
CAB18026
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 80-340 of human EIF3H (NP_003747.1).
Enables deubiquitinase activity. Contributes to translation initiation factor activity. Involved in negative regulation of proteasomal ubiquitin-dependent protein catabolic process and translational initiation. Located in extracellular exosome and membrane. Part of eukaryotic translation initiation factor 3 complex. Implicated in breast cancer; prostate cancer; and prostate carcinoma. Biomarker of prostate cancer.
Purification Method:
Affinity purification
Gene ID:
8667
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and EIF3H knockout (KO) HeLa cells, using [KO Validated] EIF3H Rabbit pAb (CAB18026) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
