null

[KO Validated] DSG2 Rabbit Polyclonal Antibody (CAB19996)

SKU:
CAB19996
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
$167 - $503
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:[KO Validated] DSG2 Rabbit Polyclonal Antibody
SKU:CAB19996
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 635-935 of human DSG2 (NP_001934.2).
Sequence:CHCG KGAK GFTP IPGT IEML HPWN NEGA PPED KVVP SFLP VDQG GSLV GRNG VGGM AKEA TMKG SSSA SIVK GQHE MSEM DGRW EEHR SLLS GRAT QFTG ATGA IMTT ETTK TARA TGAS RDMA GAQA AAVA LNEE FLRN YFTD KAAS YTEE DENH TAKD CLLV YSQE ETES LNAS IGCC SFIE GELD DRFL DDLG LKFK TLAE VCLG QKID INKE IEQR QKPA TETS MNTA SHSL CEQT MVNS ENTY SSGS SFPV PKSL QEAN AEKV TQEI VTER SVSS RQAQ KVAT PLPD PMAS RNVI A
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:2000
Synonyms:HDGC; CDHF5; G2
Positive Sample:A-549
Conjugate:Unconjugated
Cellular Localization:Cell junction, Cell membrane, Single-pass type I membrane protein, desmosome.
Calculated MW:122kDa
Observed MW:150kDa

This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10.

Purification Method:Affinity purification
Gene ID:1829
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from wild type (WT) and DSG2 knockout (KO) A-549 cells, using [KO Validated] DSG2 Rabbit pAb (CAB19996) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.

Related Products