The DPYSL2 Polyclonal Antibody (CAB14570) is a valuable tool for researchers studying the DPYSL2 protein, also known as dihydropyrimidinase-like 2. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.DPYSL2 is a cytoplasmic protein involved in neuronal development and plasticity, making it an important target for studies in neuroscience and neurology. By binding to the DPYSL2 protein, this antibody enables researchers to detect and analyze its expression in various cell types, allowing for a better understanding of its role in neuronal function and diseases such as neurodegenerative disorders.
The DPYSL2 Polyclonal Antibody is a reliable tool for researchers looking to investigate the function of DPYSL2 in a variety of contexts, from basic research in neuronal biology to the development of potential therapies for neurological conditions. Its high specificity and validation make it a valuable asset for any laboratory working in the field of neuroscience.
This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
1808
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using [KO Validated] CRMP2/DPYSL2 Rabbit pAb (CAB14570) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
