[KO Validated] CRMP2/DPYSL2 Rabbit Polyclonal Antibody (CAB14570)
- SKU:
- CAB14570
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Developmental Biology
Frequently bought together:
Description
Product Name: | [KO Validated] CRMP2/DPYSL2 Rabbit Polyclonal Antibody |
SKU: | CAB14570 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 400-500 of human CRMP2/CRMP2/DPYSL2 (NP_001377.1). |
Sequence: | RIAV GSDA DLVI WDPD SVKT ISAK THNS SLEY NIFE GMEC RGSP LVVI SQGK IVLE DGTL HVTE GSGR YIPR KPFP DFVY KRIK ARSR LAEL RGVP RGLY D |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:100 - 1:500 |
Synonyms: | DRP2; N2A3; CRMP2; DRP-2; ULIP2; CRMP-2; DHPRP2; ULIP-2; L2 |
Positive Sample: | HepG2,U-251MG,293T |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Membrane, cytoskeleton, cytosol. |
Calculated MW: | 62kDa |
Observed MW: | 62kDa |
This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method: | Affinity purification |
Gene ID: | 1808 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |