[KO Validated] DNMT3A Rabbit Monoclonal Antibody (CAB19659)
- SKU:
- CAB19659
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | [KO Validated] DNMT3A Rabbit Monoclonal Antibody |
SKU: | CAB19659 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 550-650 of human DNMT3A (Q9Y6K1). |
Sequence: | GNNN CCRC FCVE CVDL LVGP GAAQ AAIK EDPW NCYM CGHK GTYG LLRR REDW PSRL QMFF ANNH DQEF DPPK VYPP VPAE KRKP IRVL SLFD GIAT GLLV L |
Tested Applications: | WB IP ELISA |
Recommended Dilution: | WB,1:100 - 1:500 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | TBRS; HESJAS; DNMT3A2; M.HsaIIIA; 3A |
Positive Sample: | 293T |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 102kDa |
Observed MW: | 85kDa/95kDa/130kDa |
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.
Purification Method: | Affinity purification |
Gene ID: | 1788 |
Clone Number: | ARC0138 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |