[KO Validated] DIAPH1 Rabbit Polyclonal Antibody (CAB18081)
- SKU:
- CAB18081
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | [KO Validated] DIAPH1 Rabbit Polyclonal Antibody |
SKU: | CAB18081 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1158-1272 of human DIAPH1 (NP_005210.3). |
Sequence: | TEEK MRRA KLAK EKAE KERL EKQQ KREQ LIDM NAEG DETG VMDS LLEA LQSG AAFR RKRG PRQA NRKA GCAV TSLL ASEL TKDD AMAA VPAK VSKN SETF PTIL EEAK ELVG RAS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | DIA1; DRF1; DFNA1; LFHL1; SCBMS; hDIA1; mDia1; [KD Validated] DIAPH1 |
Positive Sample: | 293T |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cell projection, Cytoplasm, cytoskeleton, ruffle membrane. |
Calculated MW: | 141kDa |
Observed MW: | 150kDa |
This gene is a homolog of the Drosophila diaphanous gene, and has been linked to autosomal dominant, fully penetrant, nonsyndromic sensorineural progressive low-frequency hearing loss. Actin polymerization involves proteins known to interact with diaphanous protein in Drosophila and mouse. It has therefore been speculated that this gene may have a role in the regulation of actin polymerization in hair cells of the inner ear. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 1729 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |