The KO Validated Delta-Catenin (p120-Catenin) Rabbit Polyclonal Antibody (CAB18043) is a valuable tool for researchers studying the delta-catenin (p120-catenin) protein, an important component of cell-cell adhesion and signaling pathways. This antibody, raised in rabbits, is highly specific and reactive with human samples, making it ideal for use in Western blot applications.Delta-catenin (p120-catenin) is a critical regulator of cell adhesion and motility, playing a key role in maintaining tissue integrity and organization. Dysregulation of delta-catenin has been linked to cancer progression and metastasis, making it a promising target for cancer research.
By binding to the delta-catenin protein, this antibody enables precise detection and analysis in various cell types, providing valuable insights into its function and implications in disease.This antibody's validation for knockout (KO) studies ensures its reliability and accuracy in experiments investigating the specific role of delta-catenin in cellular processes. Its versatility and specificity make it a valuable tool for researchers in cell biology, cancer biology, and developmental biology, offering new avenues for understanding the complex mechanisms of cell adhesion and signaling.
CAS; p120; BCDS2; CTNND; P120CAS; P120CTN; p120(CAS); p120(CTN); in
Positive Sample:
HeLa
Conjugate:
Unconjugated
Cellular Localization:
Cell membrane, Cytoplasm, Nucleus.
Calculated MW:
108kDa
Observed MW:
100kDa
This gene encodes a member of the Armadillo protein family, which function in adhesion between cells and signal transduction. Multiple translation initiation codons and alternative splicing result in many different isoforms being translated. Not all of the full-length natures of the described transcript variants have been determined. Read-through transcription also exists between this gene and the neighboring upstream thioredoxin-related transmembrane protein 2 (TMX2) gene.
Purification Method:
Affinity purification
Gene ID:
1500
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and δ-Catenin/p120 Catenin knockout (KO) HeLa cells, using [KO Validated] δ-Catenin/p120 Catenin Rabbit pAb (CAB18043) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
