The KO Validated Cyclin B1 Rabbit Monoclonal Antibody (CAB19037) is a highly specific antibody designed for research involving Cyclin B1, a key protein involved in cell cycle regulation. This antibody, developed using rabbit monoclonal technology, has been validated for knockout (KO) samples and is highly reactive with human samples.Cyclin B1 is a crucial regulator of cell division and plays a pivotal role in cell cycle progression. Dysregulation of Cyclin B1 expression has been linked to various human diseases, including cancer. The KO Validated Cyclin B1 Rabbit Monoclonal Antibody (CAB19037) binds specifically to Cyclin B1, enabling accurate detection and analysis in a variety of cell types.
This antibody is ideal for use in Western blot applications, providing researchers with a reliable tool for studying the role of Cyclin B1 in cell cycle regulation and its implications in diseases such as cancer. With its high specificity and sensitivity, the KO Validated Cyclin B1 Rabbit Monoclonal Antibody (CAB19037) is a valuable asset in immunology and cancer research.
The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). The encoded protein is necessary for proper control of the G2/M transition phase of the cell cycle.
Purification Method:
Affinity purification
Gene ID:
891
Clone Number:
ARC0474
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts from wild type (WT) and Cyclin B1 knockout (KO) HeLa cells, using Cyclin B1 antibody (CAB19037) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
