The CLPP Polyclonal Antibody (CAB19975) is a valuable tool for researchers studying CLPP, a key protein involved in mitochondrial function and cell metabolism. This rabbit polyclonal antibody is highly specific for CLPP in human samples, making it ideal for Western blot applications. By detecting and analyzing CLPP protein levels in various cell types, this antibody is essential for investigations in biochemistry, cell biology, and metabolism research.CLPP is a protease enzyme found in the mitochondria, where it plays a crucial role in protein quality control and the regulation of mitochondrial function.
Dysregulation of CLPP has been linked to various diseases, including metabolic disorders and neurodegenerative conditions. By studying the expression and activity of CLPP, researchers can gain insights into mitochondrial dysfunction and potential therapeutic targets for these diseases.Overall, the CLPP Polyclonal Antibody (CAB19975) offers researchers a reliable tool to investigate the role of CLPP in mitochondrial biology and disease pathology, ultimately contributing to advancements in understanding and treating a wide range of health conditions.
Product Name:
[KO Validated] CLPP Rabbit Polyclonal Antibody
SKU:
CAB19975
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-277 of human CLPP (NP_006003.1).
The protein encoded by this gene belongs to the peptidase family S14 and hydrolyzes proteins into small peptides in the presence of ATP and magnesium. The protein is transported into mitochondrial matrix and is associated with the inner mitochondrial membrane.
Purification Method:
Affinity purification
Gene ID:
8192
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and CLPP knockout (KO) 293T cells, using [KO Validated] CLPP Rabbit pAb (CAB19975) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
