The CHD4 Polyclonal Antibody (CAB14896) is a reliable tool for researchers studying the CHD4 protein, a key chromatin remodeling factor involved in gene regulation and DNA repair processes. This antibody, raised in rabbits, has been rigorously tested and validated for use in a variety of applications, including Western blot and immunofluorescence.CHD4, also known as Chromodomain Helicase DNA-binding Protein 4, is essential for maintaining chromatin structure and regulating gene expression. Dysregulation of CHD4 has been implicated in various diseases, including cancer and developmental disorders.
By targeting CHD4 with this antibody, researchers can better understand its role in cellular processes and potentially identify new therapeutic targets for diseases associated with CHD4 dysfunction.With its high specificity and sensitivity, the CHD4 Polyclonal Antibody is an invaluable tool for advancing research in molecular biology, epigenetics, and cancer biology. By enabling precise detection and analysis of CHD4 expression and localization, this antibody facilitates in-depth studies that may lead to important discoveries in the field of chromatin remodeling and gene regulation.
Product Name:
[KO Validated] CHRAC1 Rabbit Polyclonal Antibody
SKU:
CAB14896
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-131 of human CHRAC1 (NP_059140.1).
CHRAC1 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.
Purification Method:
Affinity purification
Gene ID:
54108
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts from normal (control) and CHRAC1 knockout (KO) HeLa cells, using CHRAC1 antibody (CAB14896) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 15s.
