The CHD1 Polyclonal Antibody (CAB7883) is a valuable tool for researchers studying the CHD1 protein, a key player in chromatin remodeling and gene expression regulation. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications.The CHD1 protein is involved in modulating chromatin structure, which in turn affects gene transcription and cellular processes. By targeting the CHD1 protein, researchers can gain insight into how chromatin remodeling contributes to various biological functions, including cell differentiation, development, and disease progression.
With its high reactivity and specificity, the CHD1 Polyclonal Antibody is an essential reagent for studies in epigenetics, gene regulation, and cancer biology. By enabling the detection and analysis of CHD1 protein levels in different cell types and tissues, this antibody opens up new avenues for understanding the role of chromatin remodeling in health and disease.
Product Name:
[KO Validated] CHD1 Rabbit Polyclonal Antibody
SKU:
CAB7883
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1600 to the C-terminus of human CHD1 (NP_001261.2).
The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template.
Purification Method:
Affinity purification
Gene ID:
1105
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and CHD1 knockout (KO) 293T cells, using [KO Validated] CHD1 Rabbit pAb (CAB7883) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
