The KO Validated CD98 Polyclonal Antibody (CAB19880) is a valuable tool for research involving the CD98 protein, a key component of amino acid transport and cell adhesion processes. This antibody, produced in rabbits, has been rigorously validated for use in Western blot applications and is highly reactive with human samples.CD98, also known as 4F2 antigen heavy chain, plays a crucial role in nutrient uptake and cell signaling, making it an important target for studies in metabolism, cell growth, and cancer biology.
The CD98 Polyclonal Antibody binds specifically to the CD98 protein, allowing for precise detection and analysis in a variety of cell types.With its versatility and reliability, the CD98 Polyclonal Antibody is an essential tool for researchers investigating the function and regulation of CD98 in health and disease. Its use in immunology and cancer research can provide valuable insights into the mechanisms underlying these conditions, ultimately leading to the development of targeted therapies and treatments.
Product Name:
SLC3A2/CD98hc Polyclonal Antibody
SKU:
CAB19880
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 461-630 of human SLC3A2/CD98hc (NP_002385.3).
Apical cell membrane, Melanosome, Single-pass type II membrane protein.
Calculated MW:
58kDa
Observed MW:
75-120kDa
This gene is a member of the solute carrier family and encodes a cell surface, transmembrane protein. The protein exists as the heavy chain of a heterodimer, covalently bound through di-sulfide bonds to one of several possible light chains. The encoded transporter plays a role in regulation of intracellular calcium levels and transports L-type amino acids. Alternatively spliced transcript variants, encoding different isoforms, have been characterized.
Purification Method:
Affinity purification
Gene ID:
6520
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates, using SLC3A2/CD98hc Rabbit pAb (CAB19880) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
