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[KO Validated] CD2BP2 Rabbit Polyclonal Antibody (CAB19891)

SKU:
CAB19891
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Epigenetics and Nuclear Signaling
€139 - €419
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Description

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Product Name:[KO Validated] CD2BP2 Rabbit Polyclonal Antibody
SKU:CAB19891
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-341 of human CD2BP2 (NP_006101.1).
Sequence:MPKR KVTF QGVG DEED EDEI IVPK KKLV DPVA GSGG PGSR FKGK HSLD SDEE EDDD DGGS SKYD ILAS EDVE GQEA ATLP SEGG VRIT PFNL QEEM EEGH FDAD GNYF LNRD AQIR DSWL DNID WVKI RERP PGQR QASD SEEE DSLG QTSM SAQA LLEG LLEL LLPR ETVA GALR RLGA RGGG KGRK GPGQ PSSP QRLD RLSG LADQ MVAR GNLG VYQE TRER LAMR LKGL GCQT LGPH NPTP PPSL DMFA EELA EEEL ETPT PTQR GEAE SRGD GLVD VMWE YKWE NTGD AELY GPFT SAQM QTWV SEGY FPDG VYCR KLDP PGGQ FYNS KRID FDLY T
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:2000
Synonyms:LIN1; Snu40; FWP010; U5-52K; PPP1R59; P2
Positive Sample:293T
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Nucleus.
Calculated MW:38kDa
Observed MW:50kDa

This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined.

Purification Method:Affinity purification
Gene ID:10421
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from wild type (WT) and CD2BP2 knockout (KO) 293T cells, using [KO Validated] CD2BP2 Rabbit pAb (CAB19891) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.

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