The CCDC6 Polyclonal Antibody (CAB19901) is a valuable tool for researchers studying the cell cycle and DNA repair mechanisms. This rabbit polyclonal antibody is highly specific to CCDC6 protein and has been validated for use in Western blot applications. By targeting CCDC6, researchers can better understand its role in cell proliferation, DNA damage response, and potential implications in cancer development.CCDC6, also known as Coiled-Coil Domain Containing 6, is a key player in maintaining genomic stability and preventing tumorigenesis.
Dysregulation of CCDC6 has been linked to various types of cancer, making it a promising target for cancer research and personalized medicine. By using the CCDC6 Polyclonal Antibody, researchers can explore the mechanisms underlying CCDC6 function and potentially identify new therapeutic strategies for cancer treatment.
Product Name:
[KO Validated] CCDC6 Rabbit Polyclonal Antibody
SKU:
CAB19901
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 55-222 of human CCDC6 (NP_005427.2).
This gene encodes a coiled-coil domain-containing protein. The encoded protein is ubiquitously expressed and may function as a tumor suppressor. A chromosomal rearrangement resulting in the expression of a fusion gene containing a portion of this gene and the intracellular kinase-encoding domain of the ret proto-oncogene is the cause of thyroid papillary carcinoma.
Purification Method:
Affinity purification
Gene ID:
8030
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and CCDC6 knockout (KO) HeLa cells, using [KO Validated] CCDC6 Rabbit pAb (CAB19901) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
