The CBR1 Polyclonal Antibody (CAB18074) is a valuable tool for research involving CBR1, an enzyme involved in the metabolism of xenobiotics and endogenous compounds in the human body. This rabbit-derived antibody is highly specific and sensitive for detecting CBR1 in various biological samples, making it ideal for use in Western blot applications.CBR1 plays a crucial role in drug metabolism and detoxification processes in the liver, making it an important target for studying drug interactions and toxicity.
Additionally, CBR1 has been implicated in cancer development and progression, making it a potential therapeutic target for cancer treatment.With its high reactivity and specificity, the CBR1 Polyclonal Antibody is a valuable tool for researchers studying the role of CBR1 in various diseases and physiological processes. Its ability to detect and analyze CBR1 in different cell types makes it a versatile antibody for studies in pharmacology, toxicology, and oncology.
Product Name:
[KO Validated] CBR1 Rabbit Polyclonal Antibody
SKU:
CAB18074
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-277 of human CBR1 (NP_001748.1).
The protein encoded by this gene belongs to the short-chain dehydrogenases/reductases (SDR) family, which function as NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds, such as quinones, prostaglandins, and various xenobiotics. Alternatively spliced transcript variants have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
873
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and CBR1 knockout (KO) A-549 cells, using [KO Validated] CBR1 Rabbit pAb (CAB18074) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
