[KO Validated] Catalase Rabbit Polyclonal Antibody (CAB18018)
- SKU:
- CAB18018
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | [KO Validated] Catalase Rabbit Polyclonal Antibody |
SKU: | CAB18018 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-225 of human Catalasealase (NP_001743.1). |
Sequence: | MADS RDPA SDQM QHWK EQRA AQKA DVLT TGAG NPVG DKLN VITV GPRG PLLV QDVV FTDE MAHF DRER IPER VVHA KGAG AFGY FEVT HDIT KYSK AKVF EHIG KKTP IAVR FSTV AGES GSAD TVRD PRGF AVKF YTED GNWD LVGN NTPI FFIR DPIL FPSF IHSQ KRNP QTHL KDPD MVWD FWSL RPES LHQV SFLF SDRG IPDG HRHM NGYG SHTF KLVN A |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:3000 |
Synonyms: | CAT; catalase; MGC138422; MGC138424; se |
Positive Sample: | HeLa |
Conjugate: | Unconjugated |
Cellular Localization: | Peroxisome. |
Calculated MW: | 60kDa |
Observed MW: | 60kDa |
This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene.
Purification Method: | Affinity purification |
Gene ID: | 847 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |