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[KO Validated] CACYBP Rabbit Polyclonal Antibody (CAB20004)

SKU:
CAB20004
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Signal Transduction
$167 - $503
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Description

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Product Name:[KO Validated] CACYBP Rabbit Polyclonal Antibody
SKU:CAB20004
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-228 of human CACYBP (NP_055227.1).
Sequence:MASE ELQK DLEE VKVL LEKA TRKR VRDA LTAE KSKI ETEI KNKM QQKS QKKA ELLD NEKP AAVV APIT TGYT VKIS NYGW DQSD KFVK IYIT LTGV HQVP TENV QVHF TERS FDLL VKNL NGKS YSMI VNNL LKPI SVEG SSKK VKTD TVLI LCRK KVEN TRWD YLTQ VEKE CKEK EKPS YDTE TDPS EGLM NVLK KIYE DGDD DMKR TINK AWVE SREK QAKG DTEF
Tested Applications:WB ELISA
Recommended Dilution:WB,1:1000 - 1:2000
Synonyms:SIP; GIG5; PNAS-107; S100A6BP; BP
Positive Sample:293T
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Nucleus.
Calculated MW:26kDa
Observed MW:26kDa

The protein encoded by this gene is a calcyclin binding protein. It may be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. It probably serves as a molecular bridge in ubiquitin E3 complexes and participates in the ubiquitin-mediated degradation of beta-catenin. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Purification Method:Affinity purification
Gene ID:27101
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from wild type (WT) and CACYBP knockout (KO) 293T cells, using [KO Validated] CACYBP Rabbit pAb (CAB20004) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.

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