[KO Validated] BRD4 Rabbit Polyclonal Antibody (CAB20019)
- SKU:
- CAB20019
- Product Type:
- Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
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Description
Product Name: | [KO Validated] BRD4 Rabbit Polyclonal Antibody |
SKU: | CAB20019 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 600-722 of human BRD4 (NP_055114.1). |
Sequence: | ESEE EDKC KPMS YEEK RQLS LDIN KLPG EKLG RVVH IIQS REPS LKNS NPDE IEID FETL KPST LREL ERYV TSCL RKKR KPQA EKVD VIAG SSKM KGFS SSES ESSS ESSS SDSE DSET GPA |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | CAP; MCAP; HUNK1; HUNKI; FSHRG4; D4 |
Positive Sample: | HeLa,HeLa-BRD4-FL,HeLa-BRD4-S(a),HeLa-BRD4-S(b) |
Conjugate: | Unconjugated |
Cellular Localization: | Chromosome, Nucleus. |
Calculated MW: | 80kDa/88kDa/152kDa |
Observed MW: | 200kDa/140kDa/120kDa |
The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described.
Purification Method: | Affinity purification |
Gene ID: | 23476 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |