[KO Validated] ATOX1 Rabbit Polyclonal Antibody (CAB19925)
- SKU:
- CAB19925
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
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Description
Product Name: | [KO Validated] ATOX1 Rabbit Polyclonal Antibody |
SKU: | CAB19925 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-68 of human ATOX1 (NP_004036.1). |
Sequence: | MPKH EFSV DMTC GGCA EAVS RVLN KLGG VKYD IDLP NKKV CIES EHSM DTLL ATLK KTGK TVSY LGLE |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | ATX1; HAH1; X1 |
Positive Sample: | 293T |
Conjugate: | Unconjugated |
Cellular Localization: | cytosol |
Calculated MW: | 7kDa |
Observed MW: | 7kDa |
This gene encodes a copper chaperone that plays a role in copper homeostasis by binding and transporting cytosolic copper to ATPase proteins in the trans-Golgi network for later incorporation to the ceruloplasmin. This protein also functions as an antioxidant against superoxide and hydrogen peroxide, and therefore, may play a significant role in cancer carcinogenesis. Because of its cytogenetic location, this gene represents a candidate gene for 5q-syndrome.
Purification Method: | Affinity purification |
Gene ID: | 475 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |