[KO Validated] ATG5 Rabbit Monoclonal Antibody (CAB19677)
- SKU:
- CAB19677
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | [KO Validated] ATG5 Rabbit Monoclonal Antibody |
SKU: | CAB19677 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ATG5 (Q9H1Y0). |
Sequence: | MTDD KDVL RDVW FGRI PTCF TLYQ DEIT EREA EPYY LLLP RVSY LTLV TDKV KKHF QKVM RQED ISEI WFEY EGTP LKWH YPIG LLFD LLAS SSAL PWNI |
Tested Applications: | WB IHC-P IP ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | ASP; APG5; APG5L; hAPG5; SCAR25; APG5-LIKE; G5 |
Positive Sample: | 293T,HeLa,SH-SY5Y,Mouse brain,Mouse lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Peripheral membrane protein, Preautophagosomal structure membrane. |
Calculated MW: | 32kDa |
Observed MW: | 55kDa |
The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. Several transcript variants encoding different protein isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 9474 |
Clone Number: | ARC0156 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |