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[KO Validated] ASS1 Rabbit Polyclonal Antibody (CAB19878)

SKU:
CAB19878
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Metabolism
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:[KO Validated] ASS1 Rabbit Polyclonal Antibody
SKU:CAB19878
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-412 of human ASS1 (NP_446464.1).
Sequence:MSSK GSVV LAYS GGLD TSCI LVWL KEQG YDVI AYLA NIGQ KEDF EEAR KKAL KLGA KKVF IEDV SREF VEEF IWPA IQSS ALYE DRYL LGTS LARP CIAR KQVE IAQR EGAK YVSH GATG KGND QVRF ELSC YSLA PQIK VIAP WRMP EFYN RFKG RNDL MEYA KQHG IPIP VTPK NPWS MDEN LMHI SYEA GILE NPKN QAPP GLYT KTQD PAKA PNTP DILE IEFK KGVP VKVT NVKD GTTH QTSL ELFM YLNE VAGK HGVG RIDI VENR FIGM KSRG IYET PAGT ILYH AHLD IEAF TMDR EVRK IKQG LGLK FAEL VYTG FWHS PECE FVRH CIAK SQER VEGK VQVS VLKG QVYI LGRE SPLS LYNE ELVS MNVQ GDYE PTDA TGFI NINS LRLK EYHR LQSK VTAK
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:2000
Synonyms:ASS; CTLN1; S1
Positive Sample:HeLa
Cellular Localization:cell body fiber, cytoplasm, cytosol, endoplasmic reticulum, extracellular exosome, lysosome, mitochondrial outer membrane, nucleoplasm
Calculated MW:47kDa
Observed MW:46kDa

The protein encoded by this gene catalyzes the penultimate step of the arginine biosynthetic pathway. There are approximately 10 to 14 copies of this gene including the pseudogenes scattered across the human genome, among which the one located on chromosome 9 appears to be the only functional gene for argininosuccinate synthetase. Mutations in the chromosome 9 copy of this gene cause citrullinemia. Two transcript variants encoding the same protein have been found for this gene.

Purification Method:Affinity purification
Gene ID:445
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from wild type (WT) and ASS1 knockout (KO) HeLa cells, using [KO Validated] ASS1 Rabbit pAb (CAB19878) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.

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