The ARL6IP1 Polyclonal Antibody (CAB19995) is a valuable tool for research involving ARL6IP1, a protein that plays a role in intracellular vesicle trafficking and membrane dynamics. This rabbit polyclonal antibody is highly specific for human samples and has been validated for use in Western blot applications. By targeting the ARL6IP1 protein, researchers can study its function in various cellular processes and pathways, making it ideal for studies in cell biology and molecular biology.ARL6IP1 is known to interact with other proteins involved in vesicle transport and membrane fusion, making it a key player in intracellular trafficking mechanisms.
Research on ARL6IP1 can provide insights into how cells regulate the movement and communication of cellular components, which is crucial for understanding processes such as protein secretion and organelle maintenance.Furthermore, dysregulation of ARL6IP1 has been linked to certain diseases, including neurodegenerative disorders and cancer. Investigating the role of ARL6IP1 in these conditions can help uncover potential therapeutic targets and pathways for intervention. Overall, the ARL6IP1 Polyclonal Antibody is a valuable tool for uncovering the functions and implications of ARL6IP1 in cellular processes and disease states.
Product Name:
[KO Validated] ARL6IP1 Rabbit Polyclonal Antibody
SKU:
CAB19995
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ARL6IP1 (NP_055976.1).
This gene belongs to the ARL6ip family and encodes a transmembrane protein that is predominantly localized to intracytoplasmic membranes. It is highly expressed in early myeloid progenitor cells and thought to be involved in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation. Mutations in this gene are associated with spastic paraplegia 61 (SPG61). Alternatively spliced transcript variants have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
23204
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and ARL6IP1 knockout (KO) 293T cells, using [KO Validated] ARL6IP1 Rabbit pAb (CAB19995) at 1:5000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
