The KO-Validated ARID2 Polyclonal Antibody (CAB8601) is a powerful tool for researchers studying ARID2, a key component of the SWI/SNF chromatin remodeling complex. This antibody, raised in rabbits, has been extensively validated for use in various applications, including Western blot, immunofluorescence, and immunoprecipitation.ARID2 is involved in gene regulation and plays a crucial role in controlling cell growth and differentiation. Dysregulation of ARID2 has been linked to various diseases, including cancer, making it a promising target for therapeutic development. The KO-Validated ARID2 Polyclonal Antibody enables researchers to accurately detect and analyze ARID2 expression in different cell types, providing valuable insights into its function and potential therapeutic implications.
With its high specificity and sensitivity, the KO-Validated ARID2 Polyclonal Antibody is an essential tool for researchers in the fields of molecular biology, cancer biology, and epigenetics. Whether studying ARID2 function in normal cellular processes or disease states, this antibody offers reliable and accurate results to advance scientific understanding and discovery.
Product Name:
[KO Validated] ARID2 Rabbit Polyclonal Antibody
SKU:
CAB8601
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1586-1835 of human ARID2 (NP_689854.2).
WB,1:500 - 1:2000 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells
Synonyms:
CSS6; p200; BAF200; SMARCF3; ARID2
Positive Sample:
LO2
Conjugate:
Unconjugated
Cellular Localization:
Nucleus.
Calculated MW:
197kDa
Observed MW:
250kDa
This gene encodes a member of the AT-rich interactive domain (ARID)-containing family of DNA-binding proteins. Members of the ARID family have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation and chromatin structure modification. This protein functions as a subunit of the polybromo- and BRG1-associated factor or PBAF (SWI/SNF-B) chromatin remodeling complex which facilitates ligand-dependent transcriptional activation by nuclear receptors. Mutations in this gene are associated with hepatocellular carcinomas. A pseudogene of this gene is found on chromosome1.
Purification Method:
Affinity purification
Gene ID:
196528
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from LO2 cells, using ARID2 Rabbit pAb (CAB8601) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
