[KO Validated] APEH Rabbit Polyclonal Antibody (CAB19912)
- SKU:
- CAB19912
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Product Name: | [KO Validated] APEH Rabbit Polyclonal Antibody |
SKU: | CAB19912 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human APEH (NP_001631.3). |
Sequence: | MERQ VLLS EPEE AAAL YRGL SRQP ALSA ACLG PEVT TQYG GQYR TVHT EWTQ RDLE RMEN IRFC RQYL VFHD GDSV VFAG PAGN SVET RGEL LSRE SPSG TMKA VLRK AGGT GPGE EKQF LEVW EKNR KLKS FNLS ALEK HGPV YEDD CFGC LSWS HSET HLLY VAEK KRPK AESF FQTK ALDV SASD DEIA RLKK PDQA IKGD QFVF YEDW GENM VSKS IPVL CVLD VESG NISV LEGV PENV SPGQ AFWA PGDA GVVF |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | APH; OPH; AARE; ACPH; D3S48E; D3F15S2; DNF15S2; EH |
Positive Sample: | 293T |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 81kDa |
Observed MW: | 81kDa |
This gene encodes the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma.
Purification Method: | Affinity purification |
Gene ID: | 327 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |