[KO Validated] ANXA6 Rabbit Polyclonal Antibody (CAB18069)
- SKU:
- CAB18069
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | [KO Validated] ANXA6 Rabbit Polyclonal Antibody |
SKU: | CAB18069 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human Annexin A6/Annexin VI (NP_001146.2). |
Sequence: | MAKP AQGA KYRG SIHD FPGF DPNQ DAEA LYTA MKGF GSDK EAIL DIIT SRSN RQRQ EVCQ SYKS LYGK DLIA DLKY ELTG KFER LIVG LMRP PAYC DAKE IKDA ISGI GTDE KCLI EILA SRTN EQMH QLVA AYKD AYER DLEA DIIG DTSG HFQK MLVV LLQG TREE DDVV SEDL VQQD VQDL YEAG ELKW GTDE AQFI YILG NRSK QHLR LVFD EYLK TTGK PIEA SIRG ELSG DFEK LMLA VVKC IR |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | p68; p70; ANX6; CBP68; CPB-II; VI |
Positive Sample: | HeLa |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Melanosome. |
Calculated MW: | 76kDa |
Observed MW: | 76kDa |
Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths. It is highly similar to human annexins I and II sequences, each of which contain four such repeats. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis. Alternatively spliced transcript variants have been described.
Purification Method: | Affinity purification |
Gene ID: | 309 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |