The ANXA3 Polyclonal Antibody (CAB19861) is a valuable tool for researchers studying ANXA3, a protein involved in various cellular processes, including inflammation, cell growth, and apoptosis. This antibody, produced in rabbits, is specifically designed for use in Western blot applications and is highly reactive with human samples.ANXA3, also known as annexin A3, plays a crucial role in the regulation of inflammation and cell signaling pathways. Its dysregulation has been linked to several diseases, including cancer, cardiovascular disease, and inflammatory disorders. By targeting ANXA3 with this antibody, researchers can accurately detect and analyze the protein, allowing for a better understanding of its functions in both normal and diseased states.
This antibody is a valuable tool for studies in immunology, cancer research, and cell biology, providing researchers with the ability to investigate the role of ANXA3 in various cellular processes and disease states. By utilizing this antibody, researchers can further advance our understanding of ANXA3's involvement in disease pathogenesis and potentially identify new therapeutic targets for the treatment of ANXA3-associated disorders.
Product Name:
[KO Validated] ANXA3 Rabbit Polyclonal Antibody
SKU:
CAB19861
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-323 of human ANXA3 (NP_005130.1).
This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phopholipase A2 and cleavage of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. This protein may also play a role in anti-coagulation.
Purification Method:
Affinity purification
Gene ID:
306
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and ANXA3 knockout (KO) HeLa cells, using [KO Validated] ANXA3 Rabbit pAb (CAB19861) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
