The ANXA2 Polyclonal Antibody (CAB1572) is a valuable tool for researchers studying ANXA2, a protein involved in various cellular functions such as membrane organization, cell signaling, and inflammation. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the ANXA2 protein, this antibody allows for the detection and analysis of ANXA2 in a variety of cell types, making it ideal for studies in cell biology, signal transduction, and inflammation research.
ANXA2, also known as annexin A2, is known to play a role in processes such as cell growth, proliferation, and migration, making it a potential target for therapeutic interventions in cancer and other diseases. The antibody's ability to specifically detect ANXA2 enables researchers to investigate the functions of this protein in various cellular pathways and disease conditions. Understanding the role of ANXA2 is essential for developing targeted therapies and treatments that could benefit patients with cancer, inflammatory disorders, and other conditions.
Product Name:
Annexin A2 Polyclonal Antibody
SKU:
CAB1572
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-339 of human Annexin A2 (NP_004030.1).
This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. Annexin A2 expression has been found to correlate with resistance to treatment against various cancer forms.
Purification Method:
Affinity purification
Gene ID:
302
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using Annexin A2 Rabbit pAb (CAB1572) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
