[KO Validated] Annexin A5/Annexin V Rabbit Polyclonal Antibody (CAB1728)
- SKU:
- CAB1728
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cardiovascular
Description
Product Name: | [KO Validated] Annexin A5/Annexin V Rabbit Polyclonal Antibody |
SKU: | CAB1728 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-320 of human Annexin A5/Annexin V (NP_001145.1). |
Sequence: | MAQV LRGT VTDF PGFD ERAD AETL RKAM KGLG TDEE SILT LLTS RSNA QRQE ISAA FKTL FGRD LLDD LKSE LTGK FEKL IVAL MKPS RLYD AYEL KHAL KGAG TNEK VLTE IIAS RTPE ELRA IKQV YEEE YGSS LEDD VVGD TSGY YQRM LVVL LQAN RDPD AGID EAQV EQDA QALF QAGE LKWG TDEE KFIT IFGT RSVS HLRK VFDK YMTI SGFQ IEET IDRE TSGN LEQL LLAV VKSI RSIP AYLA ETLY YAMK GAGT DDHT LIRV MVSR SEID LFNI RKEF RKNF ATSL YSMI KGDT SGDY KKAL LLLC GEDD |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | PP4; ANX5; ENX2; CPB-I; RPRGL3; HEL-S-7; VAC-alph; V |
Positive Sample: | HepG2,HeLa,DU145,PC-3,Mouse lung |
Conjugate: | Unconjugated |
Cellular Localization: | cytoplasm, cytosol, external side of plasma membrane, extracellular exosome, extracellular region, focal adhesion |
Calculated MW: | 36kDa |
Observed MW: | 35kDa |
The Annexin 5 gene spans 29 kb containing 13 exons, and encodes a single transcript of approximately 1.6 kb and a protein product with a molecular weight of about 35 kDa.The protein encoded by this gene belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction, inflammation, growth and differentiation. Annexin 5 has also been described as placental anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4 and anchorin CII. Polymorphisms in this gene have been implicated in various obstetric complications.
Purification Method: | Affinity purification |
Gene ID: | 308 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |