The ALDH9A1 Polyclonal Antibody (CAB18098) is a valuable tool for researchers studying ALDH9A1, an enzyme involved in the metabolism of aldehydes and retinoic acid. This rabbit-derived antibody is highly specific to human ALDH9A1 and has been validated for use in Western blot applications. By binding to the ALDH9A1 protein, this antibody enables accurate detection and analysis in various cell types, making it ideal for studies in metabolic biology and drug metabolism research.ALDH9A1 is known for its crucial role in detoxifying harmful aldehydes and metabolizing retinoic acid, a form of vitamin A essential for various biological processes.
Dysregulation of ALDH9A1 has been implicated in the development of diseases like cancer, cardiovascular disorders, and neurodegenerative conditions. By studying the function of ALDH9A1, researchers can gain insights into potential therapeutic targets for these diseases and develop strategies for drug development targeting this enzyme.
Product Name:
[KO Validated] ALDH9A1 Rabbit Polyclonal Antibody
SKU:
CAB18098
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human ALDH9A1 (NP_000687.3).
This protein belongs to the aldehyde dehydrogenase family of proteins. It has a high activity for oxidation of gamma-aminobutyraldehyde and other amino aldehydes. The enzyme catalyzes the dehydrogenation of gamma-aminobutyraldehyde to gamma-aminobutyric acid (GABA). This isozyme is a tetramer of identical 54-kD subunits.
Purification Method:
Affinity purification
Gene ID:
223
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and ALDH9A1 knockout (KO) 293T cells, using [KO Validated] ALDH9A1 Rabbit pAb (CAB18098) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
