The AIP Polyclonal Antibody (CAB19969) is a valuable tool for researchers studying AIP, a protein involved in immune regulation. This rabbit-derived antibody is highly specific and reactive with human samples, making it ideal for use in Western blot applications. By binding to the AIP protein, this antibody enables the detection and analysis of AIP in various cell types, making it an essential component in immunology and cancer research.AIP, also known as aryl hydrocarbon receptor-interacting protein, plays a crucial role in immune response modulation by regulating immune cell function and inflammatory pathways. Its involvement in immune regulation makes it a key target for research into diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions.
Understanding the function of AIP is essential for the development of novel therapies that target immune pathways in these disease contexts.Overall, the AIP Polyclonal Antibody (CAB19969) is a reliable tool for researchers looking to investigate the role of AIP in immune regulation and disease pathogenesis. Its specificity and reactivity make it an essential reagent for studies aiming to unravel the complexities of immune function and identify novel therapeutic targets.
Product Name:
[KO Validated] AIP Rabbit Polyclonal Antibody
SKU:
CAB19969
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-330 of human AIP (NP_003968.3).
ARA9; XAP2; PITA1; XAP-2; FKBP16; FKBP37; SMTPHN; IP
Positive Sample:
HeLa
Conjugate:
Unconjugated
Cellular Localization:
Cytoplasm.
Calculated MW:
38kDa
Observed MW:
35kDa
The protein encoded by this gene is a receptor for aryl hydrocarbons and a ligand-activated transcription factor. The encoded protein is found in the cytoplasm as part of a multiprotein complex, but upon binding of ligand is transported to the nucleus. This protein can regulate the expression of many xenobiotic metabolizing enzymes. Also, the encoded protein can bind specifically to and inhibit the activity of hepatitis B virus. Three transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
9049
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and AIP knockout (KO) HeLa cells, using [KO Validated] AIP Rabbit pAb (CAB19969) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
