The KO Validated ADRBK1 Polyclonal Antibody (CAB1662) is a powerful tool for researchers studying ADRBK1, a protein involved in cell signaling and regulation. This antibody, produced in rabbits, is highly specific for human samples and has been rigorously tested for Western blot applications. By binding to the ADRBK1 protein, researchers can accurately detect and analyze its expression in a variety of cell types.ADRBK1, also known as beta-adrenergic receptor kinase 1, plays a vital role in regulating signaling pathways involved in cardiovascular function and neurotransmission.
Dysregulation of ADRBK1 has been implicated in various diseases, including heart failure and psychiatric disorders. By studying the function of ADRBK1, researchers can gain insights into potential therapeutic targets for these conditions.Overall, the KO Validated ADRBK1 Polyclonal Antibody (CAB1662) is a valuable tool for researchers interested in understanding the role of ADRBK1 in health and disease. Its high specificity and reliability make it an essential component of studies in cardiovascular biology, neuroscience, and drug development.
Product Name:
[KO Validated] GRK2 Rabbit Polyclonal Antibody
SKU:
CAB1662
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 440-689 of human GRK2 (NP_001610.2).
This gene encodes a member of the G protein-coupled receptor kinase family of proteins. The encoded protein phosphorylates the beta-adrenergic receptor as well as a wide range of other substrates including non-GPCR cell surface receptors, and cytoskeletal, mitochondrial, and transcription factor proteins. Data from rodent models supports a role for this gene in embryonic development, heart function and metabolism. Elevated expression of this gene has been observed in human patients with heart failure and Alzheimer's disease.
Purification Method:
Affinity purification
Gene ID:
156
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using [KO Validated] GRK2 Rabbit pAb (CAB1662) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
