The ABCF2 Polyclonal Antibody (CAB19950) is a valuable tool for research involving ABCF2, a protein that plays a role in cellular processes such as DNA repair and transport. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the ABCF2 protein, this antibody allows for the detection and analysis of ABCF2 in various cell types, making it well-suited for studies in molecular biology and cancer research.
ABCF2, also known as the ATP-binding cassette sub-family F member 2, is involved in maintaining genomic stability and protecting cells from DNA damage. Its function in cellular homeostasis makes it a key target for investigating diseases related to DNA repair deficiencies, such as cancer and neurodegenerative disorders. Understanding the role of ABCF2 in these processes is essential for developing targeted therapies and diagnostic tools for these conditions.
Product Name:
[KO Validated] ABCF2 Rabbit Polyclonal Antibody
SKU:
CAB19950
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human ABCF2 (NP_005683.2).
This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. ATP-binding cassette proteins transport various molecules across extra- and intracellular membranes. Alterations in this gene may be involved in cancer progression. Related pseudogenes have been identified on chromosomes 3 and 7.
Purification Method:
Affinity purification
Gene ID:
10061
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and ABCF2 knockout (KO) 293T cells, using [KO Validated] ABCF2 Rabbit pAb (CAB19950) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
