The KNTC1 Polyclonal Antibody (CAB13064) is specifically designed for research involving KNTC1, a protein that plays a crucial role in cell division and chromosome segregation. The antibody is raised in rabbits and is highly reactive with human samples, making it a valuable tool for studies in cell biology and cancer research. KNTC1, also known as kinetochore protein C1, is essential for proper chromosome alignment during cell division, and its dysregulation has been linked to chromosomal instability and cancer progression.
The antibody binds specifically to the KNTC1 protein, allowing for precise detection and analysis in various cell types.Understanding the role of KNTC1 in cell division is vital for uncovering new therapeutic targets for cancer treatment and developing strategies to inhibit tumor growth. The KNTC1 Polyclonal Antibody is a powerful tool for researchers seeking to delve deeper into the mechanistic details of cell division and chromosome segregation.
Product Name:
KNTC1 Rabbit Polyclonal Antibody
SKU:
CAB13064
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 900-1100 of human KNTC1 (NP_055523.1).
This gene encodes a protein that is one of many involved in mechanisms to ensure proper chromosome segregation during cell division. Experimental evidence indicated that the encoded protein functioned in a similar manner to that of the Drosophila rough deal protein.
Purification Method:
Affinity purification
Gene ID:
9735
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from 293T cells, using KNTC1 Rabbit pAb (CAB13064) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
