The KMT5A/SETD8 Rabbit Monoclonal Antibody (CAB4136) is a high-quality antibody designed for research involving the KMT5A/SETD8 protein, which plays a critical role in epigenetic regulation and cell cycle control. This antibody, generated in rabbits, is highly specific and sensitive for detecting KMT5A/SETD8 in human samples, making it an invaluable tool for studies in cancer biology and epigenetics.KMT5A/SETD8 is a histone methyltransferase that plays a key role in maintaining genome stability and regulating gene expression. Dysregulation of KMT5A/SETD8 has been linked to various types of cancer, making it a promising target for developing targeted therapies.
By using the CAB4136 antibody, researchers can accurately assess KMT5A/SETD8 levels in different cell types and tissues, providing valuable insights into its functional role in cancer development and progression.Overall, the CAB4136 antibody offers researchers a reliable tool for studying the biological functions of KMT5A/SETD8 in various cellular processes, ultimately contributing to a better understanding of epigenetic mechanisms in cancer and potential therapeutic targets.
Product Name:
KMT5A/SETD8 Rabbit Monoclonal Antibody
SKU:
CAB4136
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human KMT5A/SETD8 (Q9NQR1).
The protein encoded by this gene is a protein-lysine N-methyltransferase that can monomethylate Lys-20 of histone H4 to effect transcriptional repression of some genes. The encoded protein is required for cell proliferation and plays a role in chromatin condensation.
Purification Method:
Affinity purification
Gene ID:
387893
Clone Number:
ARC0916
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using [KD Validated] KMT5A/SETD8 Rabbit mAb (CAB4136) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
