The KLRD1 Polyclonal Antibody (CAB2039) is a valuable tool for researchers studying KLRD1, a cell surface protein involved in immune regulation and natural killer cell function. This antibody, generated in rabbits, is highly specific for human samples and is validated for use in various applications, including Western blotting.KLRD1, also known as CD94, is a key receptor in the natural killer cell receptor complex that plays a crucial role in immune surveillance and target cell recognition. By targeting KLRD1, researchers can investigate the role of natural killer cells in immune response and their potential therapeutic applications in cancer immunotherapy and infectious diseases.
The KLRD1 Polyclonal Antibody enables precise detection and analysis of KLRD1 protein expression in different cell types, making it an essential tool for immunology and cancer research. By understanding the function and regulation of KLRD1, researchers can uncover new insights into immune response modulation and develop novel therapeutic strategies for various diseases.
Product Name:
KLRD1 Rabbit Polyclonal Antibody
SKU:
CAB2039
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 32-179 of human KLRD1 (NP_002253.2).
Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. Several transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
3824
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using KLRD1 antibody (CAB2039) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
