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KLRD1 Monoclonal Antibody [PAT13E3AT] (CPAB0683)

SKU:
CPAB0683
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG1
Clone:
PAT13E3AT
Applications:
WB
ELISA
€149
Frequently bought together:

Description

system_update_alt Datasheet

KLRD1 Monoclonal Antibody [PAT13E3AT] (CPAB0683)

The KLRD1 Polyclonal Antibody (CPAB0683) is a high-quality research tool designed for studying KLRD1, a cell surface receptor involved in immune regulation and T cell function. This antibody, generated in rabbits, exhibits strong reactivity with human samples and has been validated for use in Western blotting applications. By binding specifically to the KLRD1 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an essential tool for researchers in the fields of immunology and cancer research.KLRD1, also known as CD94, plays a crucial role in regulating immune responses by interacting with HLA-E molecules and modulating NK and T cell activity.

Its involvement in immune surveillance and tolerance makes it a key target for investigating immune-related disorders, infectious diseases, and cancer immunotherapy. Understanding the function of KLRD1 is vital for developing novel therapeutic strategies that harness the immune system's potential in combating various diseases.Overall, the KLRD1 Polyclonal Antibody (CPAB0683) offers researchers a reliable tool for investigating the role of KLRD1 in immune regulation, making it an indispensable resource for studies aimed at unraveling the complexities of the immune system and developing targeted therapies for a range of diseases.

Product Name:KLRD1 Antibody
Product Sku:CPAB0683
Size:5μg
Host Species:Mouse
Immunogen:Anti-human KLRD1 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human KLRD1 protein 32-279 amino acids purified from Ecoli.
Clone:PAT13E3AT.
Reactivity:Other bodies
Applications:Western Blot, ELISA
Purification Method:KLRD1 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG1
Background:KLRD1, also known as Killer Cell Lectin Like Receptor D1, is expressed on the surface of natural killer cells in the innate immune system. KLRD1 functions as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. KLRD1 can create disulfide-bonded heterodimer with NKG2 family members. CD94 & NKG2 complex interacts with (HLA)-E, Human Leukocyte Antigen on target cells on the surface of natural killer cells.
Synonyms:Killer Cell Lectin Like Receptor D1, Killer Cell Lectin-Like Receptor Subfamily D, Member 1,  NK Cell Receptor, CD94 Antigen, CD94, KP43, Killer Cell Lectin-Like Receptor Subfamily D Member 1, Natural Killer Cells Antigen CD94,  KLRD1.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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