KLRC1 Rabbit Polyclonal Antibody (CAB1233)
- SKU:
- CAB1233
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | KLRC1 Rabbit Polyclonal Antibody |
SKU: | CAB1233 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 96-215 of human KLRC1 (NP_015567.1). |
Sequence: | RHCG HCPE EWIT YSNS CYYI GKER RTWE ESLL ACTS KNSS LLSI DNEE EMKF LSII SPSS WIGV FRNS SHHP WVTM NGLA FKHE IKDS DNAE LNCA VLQV NRLK SAQC GSSI IYHC KHKL |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | NKG2; NKG2A; CD159A; KLRC1 |
Positive Sample: | Mouse testis,Mouse liver |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Single-pass type II membrane protein. |
Calculated MW: | 26kDa |
Observed MW: | 26kDa |
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.
Purification Method: | Affinity purification |
Gene ID: | 3821 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |