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KLK3 Monoclonal Antibody [P1D10AT] (CPAB0118)

SKU:
CPAB0118
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1
Clone:
P1D10AT
Applications:
WB
ELISA
€149
Frequently bought together:

Description

system_update_alt Datasheet

KLK3 Monoclonal Antibody [P1D10AT] (CPAB0118)

The KLK3 Polyclonal Antibody (CPAB0118) is a powerful tool for researchers studying KLK3, also known as prostate-specific antigen (PSA), a key biomarker for prostate cancer diagnosis and monitoring. This antibody, derived from rabbits, exhibits high specificity and sensitivity towards human KLK3, making it ideal for applications such as Western blotting.KLK3 is a protease enzyme produced by the prostate gland and plays a crucial role in the liquefaction of semen. Elevated levels of KLK3 in the blood are indicative of prostate cancer, making it a vital target for diagnostic and prognostic purposes in clinical settings.

The KLK3 Polyclonal Antibody enables accurate detection and quantification of KLK3 levels in various biological samples, assisting researchers in understanding its role in prostate cancer development and progression. By using the KLK3 Polyclonal Antibody in their studies, researchers can gain valuable insights into the mechanisms underlying prostate cancer and potentially contribute to the development of improved diagnostic and therapeutic strategies for this prevalent form of cancer.

Product Name:KLK3 Antibody
Product Sku:CPAB0118
Size:5μg
Host Species:Mouse
Immunogen:Anti-human KLK3 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human KLK3 amino acids 25-261 purified from Ecoli.
Clone:P1D10AT.
Reactivity:Human
Applications:Western Blot, ELISA
Purification Method:KLK3 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG1
Background:Kallikrein-3 (KLK3) belongs to the kallikrein-related peptidase family. Kallikreins are a subgroup of serine proteases having various physiological functions. Numerous kallikreins are involved in carcinogenesis and some may be prospective cancer and other disease biomarkers. Kallikrein-3 is 1 of the 15 kallikrein subfamily members located in a cluster on chromosome 19 and is a protease present in seminal plasma. KLK3 hydrolyzes semenogelin-1 consequently leading to the liquefaction of the seminal coagulum. KLK3 is assumed to act normally in the liquefaction of seminal coagulum, probably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of the KLK3 protein, called PSA in the clinical setting, is beneficial in the diagnosis and monitoring of prostatic carcinoma.
Synonyms:Prostate-specific antigen, PSA, Gamma-seminoprotein, Seminin, Kallikrein-3, P-30 antigen, Semenogelase, KLK3, APS, hK3, KLK2A1.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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